GHRP-6 is an injectable peptide in the category of growth hormone releasing peptides, or GHRP’s. The most common use of these peptides is to increase GH production. Other peptides in this category include GHRP-2, hexarelin, and ipamorelin. With regard to increasing GH, all of these work similarly, and there is no need or advantage to combining them. Instead, the one most suited for the particular case is chosen.
The principal use of GHRP-6 is to provide increased GH levels, which also results in increased IGF-1 levels. This aids fat loss and in some instances aids muscle gain as well. Generally, GHRP use is chosen as an alternate to GH use, and only rarely is combined with GH.
Reasons to prefer GHRP-6 over other GHRP’s are its effect on increasing appetite (which also can be a disadvantage), and its demonstrated value in reducing inflammation and helping to heal injury, particularly tendinitis.
GHRP-6 is most generally used for the same purposes that GH might be used, but may be chosen where a cost advantage exists favoring GHRP-6, GH is not available, or the individual prefers the idea of stimulating his own GH production to injecting GH.
There is no need to cycle GHRP use, and so therefore GHRP-6 may be used whenever it is thought to be useful for any of the above reasons. However, when usage is ongoing instead of short-term amplification of a steroid cycle or fat-loss program, I recommend limiting dosage to the minimum end of the suggested dosage range.
While GHRP-6 is capable of inducing large increases in GH production when used alone, a given dose will show markedly more effect what a GHRH (growth hormone releasing hormone) peptide is taken at the same time. Alternately, when combining a GHRH with GHRP-6, only about half or a third as much GHRP-6 is needed to obtain the same increase in GH production.
For this reason, it’s a common choice to combine a GHRH with a GHRP, but excellent results are often obtained without doing so. A preferred choice of GHRH is Mod GRF 1-29 (also known as CJC-1295 without DAC.)
GHRP-6 is most commonly provided in small vials of 5 mg, which should be stored under refrigeration. (It is acceptable however for them to be mailed unrefrigerated.) The vial is diluted with a convenient volume of sterile or bacteriostatic water. For example, the vial might be diluted with 2.5 mL of water, yielding a solution of 2 mg/mL (2000 mcg/mL.) After the water addition, the vial again will be stored under refrigeration.
When dosing, an appropriate volume will be drawn from the vial with (typically) an insulin syringe, according to the desired dose and the concentration of the preparation. In the above example, a 100 mcg dose would require only 0.05 mL, or “5 IU” as marked on an insulin syringe. A 300 mcg would require 0.15 mL, or “15 IU” as marked on an insulin syringe.
Injection may be subcutaneous, intramuscular, or intravenous according to personal preference.
Dosing will ordinarily be at least twice per day and preferably 3x/day for best effect, taken at least 30-60 minutes before a meal and at a time of non-elevated blood sugar (in other words, after blood sugar has had time to fall since the most recent meal.) The amount taken generally will be from 50-300 mcg at a time. When using a GHRH along with GHRP-6, dosing should be reduced to 50-100 mcg at a time.
For increase in GH levels, higher doses within the suggested range definitely increase effect. With regard to healing benefit, for example for tendonitis, the low end of the range is often entirely sufficient and noticeably greater effect is not necessarily seen with increased dose.
While there is no sharp cut-off between a solution of GHRP-6 still being good and having lost potency with time, as a general guideline, a vial should be used within a month of having been reconstituted. Past this, I would discard the vial and start a new one.