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| Name: | Tirzepatide | CAS: | 2023788-19-2 |
|---|---|---|---|
| Molecular Formula: | C225H348N48O68 | Purity: | 99% |
| Grade: | Phamaceutical Grade | Warehouse: | US, EU, AU |
| MOQ: | 1 Box (10 Vials) | FAD: | Approved |
Factory Supply Peptide Tirzepatide: FDA-Approved GLP-1 & GIP Agonist for Diabetes & Weight Loss
Product desciption:
Tirzepatide has a greater affinity to GIP receptors than to GLP-1 receptors, and this dual agonist behavior has been shown to produce greater reductions of hyperglycemia compared to a selective GLP-1 receptor agonist. Signaling studies reported that tirzepatide mimics the actions of natural GIP at the GIP receptor. At the GLP-1 receptor, though, tirzepatide shows bias towards cAMP (a messenger associated with regulation of glycogen, sugar, and lipid metabolism) generation, rather than β-arrestin recruitment. This combination of preference towards GIP receptor and distinct signaling properties at GLP-1 suggest this biased agonism increases insulin secretion. Tirzepatide has been reported to increase levels of adiponectin, an adipokine involved in the regulation of both glucose and lipid metabolism, with a maximum increase of 26% from baseline after 26 weeks, at the 10 mg dosage.
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