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Sildenafil Viagra Erectile Dysfunction Medication Powder Cas 139755-83-2

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Certification
China Shaanxi Jeujon Bio-Tech Ltd certification
China Shaanxi Jeujon Bio-Tech Ltd certification
the product arrived & I am satisfied.

—— Kevin from USA

very good quality

—— Sotiris from Cyprus

Jason has been very helpful and understanding we had a slow start but got there in the end excellent work and thank you so much.

—— James from UK

Fast and prompt shipping and great communication.!! Testing product but so far all looks legit and will use again.

—— Joao from Australia

From start to finish the supplier kept me up to date every step of the way, great service, great product and extremely professional service. I will definitely be using this company again for future purchases.

—— John from USA

Supplier service: Very Satisfied On-time Shipment: Very Satisfied Good quality

—— Jason William from Germany

Sildenafil Viagra Erectile Dysfunction Medication Powder Cas 139755-83-2

Sildenafil Viagra Erectile Dysfunction Medication Powder Cas 139755-83-2
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Product Details:
Place of Origin: China
Brand Name: JEUJON
Certification: ISO 9001, ISO 9000, ISO 20000, QC 080000, GMP, HACCP, ISO 22000, FSC
Model Number: ED medications
Payment & Shipping Terms:
Minimum Order Quantity: 1.0 Kilogram
Price: Negotiable
Packaging Details: Double plastic bags inside, aluminium foil bag outside
Delivery Time: 1~3 working days
Payment Terms: T/T, Western Union, MoneyGram, PayPal, All Cryptocurrency (BTC, USDT, ETH, LTC, OKB, OKT, ETC...)
Supply Ability: 500kg per Month
Detailed Product Description
Product Name: Sildenafil Other Name: Revatio,Viagra
CAS: 139755-83-2 Appearance: White Powder
Usage: Treating ED Storage: Cool And Dry
Sample Order: 1.0 Kilogram Delivery: 100% Guaranteed
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Pharmacologic action:

 

Sildenafil is a selective inhibitor of cyclic guanosine phosphate (cGMP) specific type 5 phosphodiesterase (PDE5), and is an oral drug for the treatment of ED. The physiological mechanism of normal penile erection involves the release of nitric oxide (NO) during sexual stimulation Nitric oxide activates the guanosine cyclase in the smooth muscle cells of the penile cavernose, leading to an increase in the level of cGMP, which makes the smooth muscle in the sponge relax, the cavernous sinus dilates, and the blood inflow of the penis erectile dysfunction is mainly due to the smooth muscle relaxation disorder of the penile cavernose Sildenafil has no direct relaxation effect on the isolated human spongiform, but can enhance the effect of nitric oxide by inhibiting the decomposition of PDE5 to cGMP in the spongiform.

 

 

Product Description:

 

 

Product name  Sildenafil
Other names:  Revatio,Viagra
CAS NO. 139755-83-2

Appearance

White powder

Molecular formula

C22H30N6O4S
Boiling point 672.4ºC at 760 mmHg
Melting point 187-189°C

Flashing point

360.5ºC
Grade  Pharmaceutical grade

 

 

When local nitric oxide release is caused by sexual stimulation, sildenafil inhibits PDE5, which can increase the level of cGMP in the spongiform, relax the smooth muscle of the spongiform, and blood flows into the spongiform Studies have shown that erectile response increases with the increase of dose and plasma concentration. The efficacy of sildenafil can last for 4h(but is weaker than 2h). In vitro experiments have shown that sildenafil has high selectivity for PDE5, which is more than 80 times of PDE1 and 700 times of PDE4 and 4000 times of PDE3 Since PDE3 is related to the control of myocardial contractility, there is no PDE5 in the myocardium, so sildenafil has no positive inotropic effect and does not directly affect myocardial contractility However, sildenafil can cause systemic circulation vasodilation, and high dose (100mg) oral administration can lead to a decrease in supine blood pressure [average maximum reduction of 1.12/0.73kPa(8.4/5.5mmHg)], and the most significant decrease in blood pressure 1~2 hours after taking sildenafil.

 

Therefore, sexual activity may induce cardiac events at peak blood concentration The selective effect of sildenafil on PDE5 is only 10 times that on PDE6, an enzyme present in the retina. Therefore, sildenafil may cause abnormal color vision at high doses or at high blood concentrations. In addition to the smooth muscle of human spongy body, low concentrations of PDE5 have also been found in platelets, blood vessels, visceral smooth muscle and skeletal muscle Sildenafil may enhance antiplatelet aggregation (in vitro) by inhibiting PDE5 in these tissues, inhibiting platelet thrombosis (in vivo) and peripheral vasodilation (in vivo).

 

Product Photos:


Sildenafil Viagra Erectile Dysfunction Medication Powder Cas 139755-83-2 0Sildenafil Viagra Erectile Dysfunction Medication Powder Cas 139755-83-2 1
 
Certifications:
Sildenafil Viagra Erectile Dysfunction Medication Powder Cas 139755-83-2 2
 
FAQ:

Q1: Are you a manufacturer?
Answer: Yes, we are manufactuer.
 
Q2: Which kind of payment terms do you accept?
Standard terms: T/T, MoneyGram, Western Union, PayPal, Bitcoin, USDT, ETH, Litecoin, Dogecoin...
 
Q3: Can you give me a discount price?
Sure,It depends on your order qty.
 
Q4: Can I get a sample?
Yes, we welcome sample order to test and check the quality.
 
Q5: How to guarantee the Product Quality before placing orders?
Strict QC with 6 steps testing from raw material purchase to finished product.
 
Q6: How to solve the after-sale disputes?
First of all, our quality control will reduce the quality problem to near zero.
We accept Changing, Reshipping or Refunding service if any quality problem.
 
Q7: Do you guarantee the delivery?
Yes, we have our own shipping lines and we guarantee the delivery 100%.

Contact Details
Shaanxi Jeujon Bio-Tech Ltd

Contact Person: Jennifer

Tel: +8615686296679

Send your inquiry directly to us