Pharmaceutical Raw Materials Best Erectile Dysfunction Medication Dapoxetin HCL CAS 129938-20-1

Pharmaceutical Raw Materials Best Erectile Dysfunction Medication Dapoxetin HCL CAS 129938-20-1

Product Description:

Prematureejaculation, or PE, is one of the most common sex dysfunction disorders in men, with rates ranging from 20 to 30 percent, which vary by region, ethnicity and statistical criteria. At present, the drug treatment of premature ejaculation is the first choice in a variety of guidelines at home and abroad. Dapoxetin hydrochloride was developed by Elililly and had a phase I clinical trial as an antidepressant. Finally, in February 2009, Johnson & Johnson first approved the market in Finland and Sweden as a treatment for premature ejaculation. Now, dapoxetin hydrochloride has been approved in more than 60 countries and regions including China. The only drug currently approved for the treatment of premature ejaculation is a class of powerful selective serotonin reuptake inhibitors (SSRIs). As an oral drug on demand, it is quickly absorbed, quickly effective, with a short half-life, quickly cleared in the body and can avoid accumulation. Dapoxetin hydrochloride, chemically known as {(+)-(S)-N, N-dimethyl -(a)- [2(naphthyl) ethyl] phenylpropylamine hydrochloride}, is a water-soluble white to off-white powder with a relative molecular weight of 341.88 and a pKa of 8.6, which is ionic in physiological conditions and conducive to rapid systemic distribution. Dapoxetin hydrochloride belongs to SSRIs, which is similar to fluoxetin in chemical structure, function and action, while its safety and tolerability are significantly better than fluoxetin.

 
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